You should not use Opana if you have severe asthma or breathing problems, a blockage in your stomach or intestines, or moderate to severe liver disease.
Oxymorphone can slow or stop your breathing, and may be habit-forming. MISUSE OF THIS MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.
Taking this medicine during pregnancy may cause life-threatening withdrawal symptoms in the newborn.
Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.
You should not take Opana if you are allergic to oxymorphone, or if you have:
- severe asthma or breathing problems;
- a blockage in your stomach or intestines; or
- moderate to severe liver disease.
To make sure Opana is safe for you, tell your doctor if you have ever had:
- any type of breathing problem or lung disease;
- head injury, brain tumor, or seizures;
- drug or alcohol addiction, or mental illness;
- urination problems;
- liver or kidney problems; or
- problems with your gallbladder, pancreas, or thyroid.
Some medicines can interact with oxymorphone and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take stimulant medicine, herbal products, or medicine for depression, mental illness, Parkinson’s disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.
If you use oxymorphone while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.
It is not known whether oxymorphone passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Get emergency medical help if you have any signs of an allergic reaction to Opana: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Like other narcotic medicines, oxymorphone can slow your breathing. Death may occur if breathing becomes too weak.
A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.
Call your doctor at once if you have:
- weak or shallow breathing;
- a light-headed feeling, like you might pass out;
- seizure (convulsions);
- chest pain, wheezing, cough with yellow or green mucus;
- severe vomiting; or
- low cortisol levels – nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Serious side effects may be more likely in older adults and those who are malnourished or debilitated.
Long-term use of opioid medication may affect fertility (ability to have children) in men or women. It is not known whether opioid effects on fertility are permanent.
Common Opana side effects may include:
- stomach pain, nausea, vomiting, constipation, diarrhea;
- dizziness, drowsiness, headache, tired feeling;
- dry mouth, increased sweating;
- sleep problems (insomnia); or
- mild rash or itching.